In 1997, Dr Jennifer Luke showed that fluoride accumulation in the pineal gland of laboratory animals reduces melatonin production by the gland, resulting in earlier onset of puberty.

In 2001, Luke  showed that fluoride accumulates in the human pineal gland (up to 21,000 ppm).

Earlier onset of menstruation in girls was also identified in fluoridated Newburgh compared with non-fluoridated Kingston (by 5 months) in the original 1945-1955 trial.

It is suggested that the risk of breast cancer is related to the time between first menstruation and first pregnancy. If so, earlier onset of puberty for girls will, other things being equal, increase the risk of breast cancer later in life.

Melatonin is also involved in sleep cycles. Disrupted sleep causes reduced immunity to disease.

Fluoridation promoters dismiss this as “just one study – there has been no follow up.”

Dr Luke has stated she finds it “astonishing” that no follow up research has been done, given the serious implications of her research.

Of course, the York Review noted that those who promote fluoridation never do research into adverse effects from fluoridation – they just try to prove it works (so far, unsuccessfully).